Probiotic/ Ibuprofen Study | Atlantia Food Clinical Trials


Probiotic/ Ibuprofen Study

We are investigating the effects of probiotics against damage in the small intestine caused by Ibuprofen

Refer a friend! We are now offering $50 for each person you refer over to us, that ends up participating in the study.

Eligibility Criteria

  • Aged 18-40
  • Not currently taking any medications or supplements *exceptions listed below*
  • Willing to avoid consuming medications and probiotic supplements for the duration of the study

Please complete the Pre-Screening Questionnaire to help us determine your eligibility for the trial
Please note, we have paused screening clinic visits for this study until Jan 2021 but you can still apply and we will be in touch in the New Year.

Study Animation
Study Info
  • Non-Steroidal-Anti-Inflammatory Drugs (NSAIDs), such as Ibuprofen, are commonly used worldwide, both as prescription-only medicines and as “over-the-counter” medications. They are often used in the treatment of many common pain-related conditions, including headaches and menstrual pain, and for long-term treatment of chronic inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Long-term use of low-dose NSAIDS are also recommended and prescribed for their heart-protecting properties.
  • However, low dose use of NSAIDS, such as ibuprofen, is associated with damage to the stomach and intestines.
  • Live bacteria formulated as probiotics may offer a safe alternative to prevent negative side effects of NSAIDS, such as ibuprofen. Probiotic bacteria have been demonstrated to have possible healing effects against intestinal inflammation among long-term ibuprofen users.
  • The goal of this study is to explore the ability of a probiotic to reduce and/or reverse ibuprofen-induced small intestinal damage and GI symptoms in healthy volunteers.
  • This study is placebo controlled. This means that you are randomly assigned to get the active product (the probiotic) or the non-active product (placebo, contains no probiotic).
Visit Info
  • A blood sample will be taken at all visits to our clinic
  • You will be required to provide a stool sample at visits 2-6
  • For women of childbearing age, a urine sample and pregnancy test will be performed
Allowed medications & supplements


  • Anti-anxiety
  • Anti-depressant
  • Anti-histamine
  • Contraception
  • Inhaler



  • General multivitamin

VCE uses a very small camera (approx. size of a supplement capsule) to take pictures of your gastrointestinal tract. The camera captures thousands of pictures over 8 hours as it passes through your system, which are then sent to a signal receiver belt that is strapped to your chest. The device has the ability to detect small intestinal inflammation & damage.

The procedure for the study visits is as follows:

  • You must fast from 12 noon, the day before each visit (liquids such as water, clear broth and decaffeinated tea/coffee are allowed)
  • At the visit the receiver belt will be strapped to your upper body
  • You will take a spoonful of Simeticone which prevents any bubbles in the small intestine and aids viewing of images from VCE
  • You will then swallow the VCE with a glass of water
  • You may leave the clinic after this point but must not consume food for 4 hours and you must keep physically active
  • You must return to the clinic after 8 hours, at which time the receiver will be removed
  • The VCE passes out naturally
COVID-19 Safety Measures

We realise that safety is the most important thing on everyone's mind right now. Click the link below to watch our vid for our safety measures to keep you and our staff safe when in our clinic. 


If you recommend a family member or a friend to us, you will receive $50 if they are eligible and end up taking part in the study. 

To refer someone:

  1. Tell them about our study.
  2. If they are interested in taking part, tell them to apply via the link above on our website or they can contact us directly if they prefer. 
  3. Email, call or DM us to let us know that you have referred them.

Note: You don't have to be participating yourself to receive the referral fee & there is no limit to the number of referrals, you can refer as many people as you like. 

All participants will receive reimbursement of $1,200 upon completion of the study.

Study visits take place in Atlantia Food Trials in 142. E. Ontario Suite 1200, Chicago, Illinois, 60611, USA.

For further information: