Can in vitro models be successfully utilized to ensure validity of a prebiotic Human Clinical Trial?

Findings of a recent study conducted by researchers of APC Microbiome Ireland showed significant benefit of utilizing a scientifically validated in vitro gut model (M-SHIME) prior to a human clinical trial. The in vitro analysis conducted by Duysburgh et al.

The human microbiome and its interaction with the immune system is a well researched topic. However, past knowledge seems to become outdated.  

Dr. Liam O'Mahony and Dr. John MacSharry, researchers at APC Microbiome Ireland and research partners of Atlantia take the stage for this in depth webinar.

Health claims within the EU is a well discussed and well researched topic.

The article, Efficacy of Isomaltulose Compared to Sucrose in Modulating Endothelial Function in Overweight Adults, has been published earlier this year in the journal Nutrients.

Ted Dinan, Emeritus Professor of Psychiatry and a Principal Investigator in APC Microbiome Ireland at University College Cork, has joined as Medical Director of Atlantia Food Clinical Trials Ltd. This decision shows the company’s appetite to engage with emergent markets segments such as live therapeutics.

The WHO, World Health Organisation, has released a new report stressing the importance of nutrition in healthcare. “Stronger focus on nutrition within health services could save 3.7 million lives by 2025”, the organisation states. This new report complies the most relevant nutrition interventions that could contribute to the achievement of the Sustainable Development Goals relevant to the nutritional field, and associated targets. Those are:

FDA has announced recent approvals in June. We would like to highlight the approval granted to EPA and DHA Omega-3 supplements as well as to a treatment for paediatric patients.  The Victoza (liraglutide) injection is a form of treatment for paediatric patients who are 10 years and older and who are diagnosed with type 2 diabetes. Type 2 diabetes is the most common form of diabetes, occurring when the pancreas cannot make enough insulin to keep blood sugar at normal levels.

World Microbiome Day is an annual event that is about creating awareness around the world of microbes.  This annual event was launched last year by the APC Microbiome Ireland, a national institute with which Atlantia is delighted to be close partners with. The theme of this years World Microbiome Day is ‘Bacterial Resistance to Antibiotics’.